Multiple mutations in polyketide synthase led to disruption of Psittacofulvin production across diverse parrot species
Abstract Polyketide synthases (PKSs) are face scrub crucial multidomain enzymes in diverse natural product biosynthesis.Parrots use a type I PKS to produce a unique pigment called psittacofulvin in their feathers.In domesticated budgerigars and lovebirds, the same amino acid substitution (R644W) within malonyl/acetyltransferase (MAT) domain of this